Microneedling with Insulin: A New Approach to Reducing Acne Scars

17 February 2025

Acne scars can be a frustrating reminder of past breakouts, often affecting confidence and skin texture. While there are various treatments available, microneedling has become one of the most popular options due to its ability to stimulate the skin’s natural healing process. Recent research suggests that using topical insulin with microneedling may be just as effective as hyaluronic acid in improving atrophic (indented) acne scars.

How Microneedling Works

Microneedling involves using a device with tiny needles to create controlled micro-injuries in the skin. This process stimulates collagen and elastin production, helping to repair damaged skin and smooth out scars over time. It also enhances the absorption of topical treatments applied immediately after the procedure.

The Role of Insulin in Skin Repair

While insulin is commonly known for its role in blood sugar regulation, it also has regenerative properties that can benefit the skin. When applied topically after microneedling, insulin may speed up healing, reduce inflammation, and promote collagen production—leading to smoother, healthier skin.

What the Research Says

A recent split-face study by Mohamed et al. (2024) compared microneedling with topical insulin and microneedling with non-cross-linked hyaluronic acid for treating atrophic acne scars. The study included 30 patients, with one side of the face treated with insulin and the other with hyaluronic acid over six sessions.

Both treatments showed statistically significant improvements in acne scar appearance.
The difference between the two sides was not significant, meaning insulin was just as effective as hyaluronic acid.
Patients were satisfied with the results, with an average improvement of nearly 50% in their acne scars.

What This Means for You

If you’re considering microneedling for acne scars, topical insulin could be a promising option. It offers a safe and effective way to enhance skin healing and improve scar texture, just like hyaluronic acid. However, more studies are needed to fully understand its long-term benefits.

For those interested in microneedling treatments, consulting with an experienced aesthetic doctor can help determine the best approach for your skin type and concerns.

Stay tuned to our weekly news updates for more insights to keep your skincare routine safe, effective, and up-to-date.

Source:

1. Mohamed SH, Omar GA, Hamdy AE. Microneedling with Topical Insulin Versus Microneedling with Non-Cross-Linked Hyaluronic Acid for Atrophic Post-Acne Scars: A Split-Face Study. PMC11313770, PMID: 39122500.